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Segmentation Confidence for Arbitrary CNNs

Baris Oguz, Xing Yao, Claudia Tawil, Alison Pouch, Brett Byram, Gabriel Arenas, Nadav Schwartz, Ipek Oguz

Latestcs.CLcs.LGcs.AIcs.CV
arXiv ID
2610.37431 v1
Category
Submitted
2026-10-27

Abstract

Convolutional neural networks (CNN) are widely used for medical image segmentation. However, they lack an inherent measure of confidence. Existing methods for estimating prediction uncertainty often require a custom network architecture and/or dedicated training setups and need to be trained from scratch. In addition, the deduction of a single confidence score per input from the uncertainty maps is not always straightforward. In this study, we explore voxel-based uncertainty estimation methods that can be added to existing segmentation pipelines without training from scratch. We also propose a novel method to estimate a single confidence score from the uncertainty maps. Our evaluations on different ROIs and modalities suggest that our confidence score can predict segmentation performance in unseen data.

Comment: 5 pages, 6 figures, published in ISBI 2026

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